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. Author manuscript; available in PMC: 2023 Jun 29.
Published in final edited form as: J Perinatol. 2020 Jul 15;40(11):1671–1678. doi: 10.1038/s41372-020-0728-8

Table 4.

Comparison of prenatal, neonatal, and NEC data of infants born at 31 weeks’ gestation

All infants (n=90) <31 weeks (n=75) >31 weeks (n=15) p-value
Prenatal information
Pregnancy-induced hypertension, n (%) 18 (24%) 7 (46.67%) 0.07
Chorioamnionitis, n (%) 5 (6.67%) 0 (0%) 0.3
Antenatal steroids, n (%) 38 (50.67%) 6/15 (40%) 0.45
Maternal Indomethacin, n (%) 2 (2.67%) 0 (0%) 0.52
Infant Demographics
Birth weight (grams; mean ± SEM) 851.43±29.71 1763.6±72.93 <0.001
Gestational age (weeks; mean ± SEM) 25.98±0.24 33.41±0.36 <0.001
Small for gestational age, n (%) 45 (60%) 7 (46.67%) 0.34
Male gender, n (%) 45 (60%) 11 (73.3%) 0.33
African American ethnicity 68 (90.67%) 12 (80%) 0.23
C-section delivery 42 (56%) 6 (40%) 0.26
Outborn 37 (49.33%) 8 (53.33%) 0.77
Infant medical information prior to NEC
5 min Apgar score 0–5, n (%) 14 (18.67%) 2 (13.33%) 0.62
Start enteral feedings (days, mean ± SEM) 2±0.49 2.1±0.3 0.92
Enteral feedings      
 Mother’s own/donor milk, n (%) 35 (47%) 9 (60%) 0.34
 Infant formula, n (%) 40 (53%) 6 (40%) 0.34
Patent Ductus Arteriosus, n (%) 40 (53.33%) 2 (13.33%) 0.005
Patent Ductus Arteriosus, medically treated, n (%) 15 (37.5%) 0 (0%) 0.39
Patent ductus arteriosus, surgically ligated, n (%) 2 (2.67%) 0 (0%) 0.52
Necrotizing enterocolitis
NEC age onset (days; mean ± SEM) 27.35±3.59 37.6±7 0.023
Length bowel resected (centimeters; mean ± SEM) 27.51±2.74 13.57±1.47 0.034
Pressor support 24h after NEC onset, n (%) 45 (60%) 10 (66.67%) 0.63
Post-operative Ileus (days; mean ± SEM) 16.75±1.45 17.64±1.83 0.55
Days of PN (days; mean ± SEM) 89.93±5.47 77.64±9.62 0.47
Day of starting feeds (days; mean ± SEM) 16.85±1.42 18.08±1.89 0.55
Day to reach full feeds (days; mean ± SEM) 80.89±5.32 59±4.45 0.2
Antibiotic days (days; mean ± SEM) 8.28±0.93 5.96±0.9 0.013
Mortality, n (%) 34 (37.8%) 4 (26.7%) 0.18
Length of hospital stay (days; mean ± SEM) 143.42±10.12 83.27±9.9 0.014