Table 4a.

Multivariable linear mixed model analysis of the relationship between hsCRP at baseline and change in PTSD scores between baseline and 6 months, stratified by race.

	Total PTSD Score				Re-experiencing Subscale
	Beta	(95% CI)	P	Interaction P-value	Beta	(95% CI)	P	Interaction P-value
Model 1: Demographics (age, sex, education)
Black	2.56	(0.66,9.97)	0.175	0.166	2.14	(1.34,3.42)	0.002	0.037
Non-Black	0.58	(0.13,2.53)	0.467		0.97	(0.59,1.6)	0.915
Model 2: Demographics + Clinical Severity (Ejection Fraction, STEMI)
Black	2.48	(0.63,9.97)	0.194	0.163	2.12	(1.31,3.42)	0.003	0.036
Non-Black	0.52	(0.11,2.34)	0.387		0.93	(0.56,1.55)	0.778
Model 3: Demographics + Severity + CV Risk Factors (BMI, Ever Smoker, Diabetes, Cholesterol, Hypertension)
Black	2.53	(0.63,10.07)	0.188	0.144	2.14	(1.32,3.46)	0.002	0.031
Non-Black	0.47	(0.1,2.12)	0.320		0.9	(0.54,1.49)	0.685
Model 4: Demographics + Severity + Risk Factors + Prescriptions (Statins, Aspirin, Antidepressants)
Black	2.64	(0.66,10.59)	0.167	0.137	2.16	(1.34,3.49)	0.002	0.029
Non-Black	0.53	(0.12,2.44)	0.411		0.93	(0.56,1.57)	0.792

Abbreviations.

PTSD: Post-Traumatic Stress Disorder.

hsCRP: High Sensitivity C-Reactive Protein.

STEMI: ST-Segment Elevation Myocardial Infarction.

CV: Cardiovascular.

BMI: Body Mass Index.

The natural log of hsCRP at baseline was used as a predictor of change in PTSD scores; then, results were transformed back to original units to ease interpretation. The beta coefficients refer to the interaction between hsCRP and time, therefore expressing the unit change in PTSD scale scores between baseline and 6 months per each unit increase in baseline hsCRP. The interaction p-value is the p-value for the three-way interaction between hsCRP, time, and race. Bolded text indicates significant results at p < 0.05.