Fig. 1.

Behavioural assessment of mice chronically infected by distinct T. gondii strains. The data represented here is from behavioural analysis for 8 weeks post-infection. (A) data analysis from the open field test, showing the total distance travelled (in meters) by non-infected (blue) and ME49- (orange) and CK2-infected (dark red) mice (left); and time spent in the periphery of the apparatus (right). (B) Data analysis from the elevated plus maze test, showing the number of entries (left) and the time spent (right) in the open arms by non-infected (blue) and ME49- (orange) and CK2-infected (dark red) mice. (C) Data analysis from the forced swim test, showing the time (in seconds) of immobility. (D) Memory analysis performed by the object recognition task. The statistical analysis for the recognition index with 50% cut-off was performed by one sample t-test. * Indicates the statistical difference between non-infected and infected mice groups; # indicates the statistical difference between the infected mice groups. Statistical analysis to find difference among the studied groups was performed using ANOVA test of variance followed by Tukey post-test. Outlier values were removed after ROUT test for outlier identification. Data presented here are expressed as mean ± standard deviation (SD). Non-infected group (n = 10); ME49-infected group (n = 13) and CK2-infected group (n = 10). */#p < 0.05; **/##p < 0.01; ***/###p < 0.001; ****/####p < 0.0001. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)