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. 2023 Jun 10;30:100652. doi: 10.1016/j.bbih.2023.100652

Fig. 7.

Fig. 7

Toxoplasma gondii chronic infection impacts the levels of neurotrophic factors and inflammatory mediators in different brain regions. Quantification of (A) nerve growth factor (NGF) and (B) glia derived neurotrophic factor (GDNF) levels in the prefrontal cortex, striatum, and hippocampus of non-infected (N = 7; blue) and ME49- (N = 7; orange) and CK2-infected (N = 7; dark red) mice. Quantification of IFN-γ (C), nitric oxide (D) and fractalkine – CX3CL1 (E) in the prefrontal cortex, striatum, and hippocampus of non-infected (blue) and ME49- (orange) and CK2-infected (dark red) mice. Data presented here are expressed as mean ± standard deviation (SD). Outlier values were removed after ROUT test for outlier identification. * Indicates the statistical difference between non-infected and infected mice groups; # indicates the statistical difference between the infected mice groups. Statistical analysis was performed using ANOVA test of variance followed by Tukey post-test. NO: nitric oxide. */#p < 0.05; **/##p < 0.01; ***/###p < 0.001; ****/####p < 0.0001. (For interpretation of the references to color in this figure legend, the reader is referred to the Web version of this article.)