TABLE 3.
Multivariable-adjusted1 mean concentration (95% CI) of serum biomarkers of glycemia measures in tertiles of EDIP-HALST scores among participants who did not take diabetic medications
| Men |
Women |
|||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| T1 (n = 714) |
T2 (n = 738) |
T3 (n = 715) |
P-quadratic2 | FDR P value | T1 (n = 838) |
T2 (n = 824) |
T3 (n = 827) |
P-quadratic2 | FDR P value | |||||||
| Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | Mean | 95% CI | |||||
| HbA1c (%) | 5.91 | (5.83, 6.00) | 5.89 | (5.81, 5.98) | 5.88 | (5.80, 5.96) | 0.90 | 0.99 | 6.03 | (5.90, 6.16) | 6.01 | (5.89, 6.14) | 6.03 | (5.90, 6.16) | 0.49 | 0.49 |
| Fasting glucose (mg/dL) | 104 | (102, 106) | 103 | (101, 105) | 103 | (101, 105) | 0.99 | 0.99 | 104 | (101, 107) | 104 | (101, 107) | 104 | (101, 108) | 0.48 | 0.49 |
| Insulin (μIU/mL) | 4.70 | (4.38, 5.05) | 5.12 | (4.78, 5.48) | 4.86 | (4.54, 5.20) | 0.01 | 0.04 | 5.02 | (4.49, 5.62) | 5.26 | (4.71, 5.87) | 5.18 | (4.64, 5.78) | 0.25 | 0.49 |
Abbreviations: EDIP, empirical dietary inflammatory pattern; FDR, false-discovery rate; HALST, the Healthy Aging Longitudinal Study in Taiwan.
Means were adjusted for age at recruitment (continuous), center, education (low literacy, primary school, middle school and above), smoking (never, former, and current), alcohol consumption (never, former, and current), physical activity at leisure time and at work (sex-specific quartile), BMI (<18.5, 18.5–25, 25–30, and ≥30 kg/m2), treatment for dyslipidemia (yes and no), and hypertension (yes and no). The dependent variables were log-transformed before fitting a multiple linear regression. The adjusted means were then calculated by exponentiating the adjusted natural-log transformed means.
The P value for the linear trend was calculated by modeling the median values of each category as a continuous variable and adjusted for all covariates listed in footnote 1.