Table 1. Baseline Characteristics of Plasmapheresis and Conventional Groups Before and After Propensity Score Matching.
| Characteristics | Participants before matching, No. (%) | Participants after matching, No. (%) | ||||
|---|---|---|---|---|---|---|
| Plasmapheresis (n = 56) | Conventional (n = 211) | P value | Plasmapheresis (n = 47) | Conventional (n = 47) | P value | |
| Age, median (IQR), y | 36.5 (31.5-43.0) | 37.0 (31.0-44.0) | .96 | 36.5 (31.8-43.0) | 37.0 (28.5-43.0) | .76 |
| Sex | ||||||
| Male | 33 (59) | 152 (72) | .06 | 29 (62) | 30 (64) | >.99 |
| Female | 23 (41) | 59 (28) | 18 (38) | 17 (36) | ||
| BMI, mean (SD)a | 27.3 (4.1) | 27.9 (4.4) | .70 | 28.0 (3.8) | 26.8 (3.3) | .95 |
| Smoking | 26 (46) | 73 (35) | .12 | 22 (47) | 14 (30) | .14 |
| Drinking | 23 (41) | 76 (36) | .54 | 21 (45) | 17 (36) | .53 |
| Acute pancreatitis history | 28 (50) | 120 (57) | .37 | 25 (53) | 33 (70) | .14 |
| Academic hospital | 53 (95) | 196 (93) | .77 | 44 (94) | 40 (85) | .32 |
| APACHE II score, median (IQR) | 9.0 (6.0-14.0) | 4.0 (2.0-7.0) | <.001 | 7.0 (4.0-12.0) | 8.0 (5.8-11.0) | >.99 |
| APACHE II ≥8 | 33 (59) | 43 (20) | <.001 | 24 (51) | 23 (49) | >.99 |
| SOFA score, median (IQR) | 2.0 (1.0-4.0) | 1.0 (0.0-2.0) | <.001 | 2.0 (0.0-3.0) | 2.0 (1.0-3.0) | .85 |
| Respiratory failure | 24 (43) | 46 (22) | <.001 | 17 (36) | 19 (40) | .83 |
| Circulatory failure | 6 (11) | 1 (1) | <.001 | 1 (2) | 0 | >.99 |
| Kidney failure | 8 (14) | 14 (7) | .12 | 5 (11) | 5 (11) | >.99 |
| SIRS score, median (IQR) | 7.0 (5.0-10.0) | 5.0 (3.0-7.0) | <.001 | 7.0 (5.0-7.8) | 5.0 (4.0-9.5) | .71 |
| CTSI score, median (IQR) | 2.0 (2.0-4.0) | 2.0 (1.0-4.0) | .54 | 2.0 (2.0-3.8) | 4.00 (2.0-6.0) | .17 |
| TG, median (IQR), mmol/L | 23.8 (16.9-36.5) | 20.9 (15.9-30.9) | .13 | 23.2 (16.9-29.6) | 24.5 (17.8-38.5) | .88 |
| CRP, median (IQR), mg/L | 128.9 (26.4-193.6) | 36.9 (8.4-125.4) | .009 | 145.4 (52.5-238.8) | 164.9 (90.6-250.2) | .35 |
| PCT, median (IQR), ug/L | 1.9 (0.3-6.2) | 0.3 (0.1-1.2) | .001 | 3.6 (0.1-9.0) | 1.1 (0.3-2.9) | .83 |
| Triglyceride-lowering therapies | ||||||
| Insulin | 46 (82) | 177 (84) | .84 | 38 (81) | 42 (89) | .39 |
| Heparin | 49 (8) | 176 (83) | .54 | 42 (89) | 36 (77) | .17 |
| Fasting | 56 (100) | 211 (100) | NA | 47 (100) | 47 (100) | NA |
Abbreviations: APACHE, Acute Physiology and Chronic Health Evaluation; BMI, body mass index; CRP, C-reactive protein; CTSI, computed tomography severity index; NA, not applicable; PCT, procalcitonin; SIRS, systemic inflammatory response syndrome; SOFA, Sequential Organ Failure Assessment; TG, triglyceride.
SI conversions: To convert CRP to milligrams per liter, multiply by 10; TG to milligrams per deciliter, divide by 0.0113.
a
Body mass index is calculated as weight in kilograms divided by height in meters squared.