Skip to main content
. 2023 Jun 9;12(3):139–152. doi: 10.5492/wjccm.v12.i3.139

Table 1.

Different methods of mensuration of mitochondrial damage and recovery

Item Description
Mitochondrial biogenesis PPAR-γ coactivator 1-α, nuclear respiratory factor 1, mitochondrial transcription factor A. Material obtained from tissue biopsy or from peripheral PBMC
Mitochondrial content Mitochondrial mass, concentration and area
Mitochondrial DNA content PGC-1α, NRF-1, absolute DNA number of copies
Mitochondrial fusion Mitofusins 1 and 2, optic atrophy 1 protein
Mitochondrial fission Dynamin-related protein 1 and fission 1 protein

PPAR-γ: Peroxisome proliferator-activated receptor gamma; PGC-1α: Peroxisome proliferator-activated receptor gamma coactivator-1 alpha; NRF-1: Nuclear respiratory factor-1; PBMC: Peripheral blood mononuclear cells.