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. 2021 Aug 12;105(5):1221–1233. doi: 10.1093/biolre/ioab152

Figure 4.

Figure 4

MiR-126 was involved in METTL3-mediated cell migration and invasion. (A) Migrating and invasive abilities of HESCs transfected with the negative control and METTL3-overexpressing vector were evaluated in the absence or presence of miR126 inhibitor (the panel above, scale bar = 100 μm). The migrating and invasive abilities of HESCs transfected with the negative control and siRNAs targeting METTL3 were evaluated in the absence or presence of miR126 mimics (the panel below, scale bar = 100 μm). (B) Number of migrating and invasive cells was presented. All experiments were repeated in triplicate or quadruplicate. Data with error bars are presented to indicate the mean ± SEM values. ***P < 0.001, and ****P < 0.0001.