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. 2023 Apr 10;48(1):287–296. doi: 10.1159/000530209

Table 3.

Top 50 metabolites correlation with mGFR

Metabolites R p value VIP
1 Hydroxyasparagine −0.96 <0.01 1.34
2 N6-carbamoylthreonyladenosine −0.96 <0.01 1.46
3 3-(3-Amino-3-carboxypropyl)uridine −0.96 <0.01 1.51
4 Gulonate −0.96 <0.01 1.76
5 2,3-Dihydroxy-5-methylthio-4-pentenoate (DMTPA) −0.95 <0.01 1.48
6 C-glycosyltryptophan −0.95 <0.01 1.44
7 Pseudouridine −0.95 <0.01 1.32
8 N-acetylserine −0.95 <0.01 1.32
9 Arabonate/xylonate −0.94 <0.01 1.59
10 S-adenosylhomocysteine (SAH) −0.94 <0.01 1.43
11 Glucuronate −0.93 <0.01 1.56
12 4-Acetamidobutanoate −0.93 <0.01 1.58
13 N-acetylhistidine −0.93 <0.01 1.35
14 1-Methyl-4-imidazoleacetate −0.93 <0.01 1.46
15 Gamma-CEHC glucuronide −0.93 <0.01 2.14
16 N,N-dimethyl-pro-pro −0.93 <0.01 1.34
17 N2,N2-dimethylguanosine −0.93 <0.01 1.38
18 Quinolinate −0.93 <0.01 1.34
19 Arabitol/xylitol −0.93 <0.01 1.44
20 Creatinine −0.93 <0.01 1.10
21 Homocitrulline −0.93 <0.01 1.66
22 N1-methylinosine −0.93 <0.01 1.56
23 5-Methylthioribose −0.92 <0.01 1.28
24 N,N,N-trimethyl-alanylproline betaine (TMAP) −0.92 <0.01 1.36
25 Vanillactate −0.92 <0.01 1.96
26 Erythronate −0.92 <0.01 1.36
27 Gluconate −0.92 <0.01 1.53252
28 Hydroxy-N6,N6,N6-trimethyllysine −0.92 <0.01 1.48
29 Orotidine −0.92 <0.01 1.53
30 O-sulfo-l-tyrosine −0.92 <0.01 1.34
31 5-(Galactosylhydroxy)-l-lysine −0.91 <0.01 1.39
32 N4-acetylcytidine −0.91 <0.01 1.40
33 Heptenedioate (C7:1-DC) −0.91 <0.01 1.50
34 N-formylmethionine −0.91 <0.01 1.13
35 Pimeloylcarnitine/3-methyladipoylcarnitine (C7-DC) −0.91 <0.01 1.62
36 1-Ribosyl-imidazoleacetate −0.91 <0.01 1.66
37 2-Methylcitrate/homocitrate −0.91 <0.01 1.28
38 N-acetyl-2-aminoadipate −0.91 <0.01 1.56
39 Kynurenate −0.90 <0.01 1.36
40 Glutamine conjugate of C6H10O2 (1) −0.90 <0.01 1.65
41 N-acetylmethionine −0.90 <0.01 1.19
42 N-acetylalanine −0.90 <0.01 1.00
43 Mannonate −0.90 <0.01 1.42
44 N-acetyl-isoputreanine −0.90 <0.01 1.30
45 Guaiacol sulfate −0.90 <0.01 2.01
46 Alpha-CEHC glucuronide −0.89 <0.01 2.02
47 Suberate (C8-DC) −0.89 <0.01 1.72
48 8-Methoxykynurenate −0.89 <0.01 1.89
49 2-Hydroxysebacate −0.89 <0.01 1.86
50 3-Hydroxy-3-methylglutarate −0.89 <0.01 1.32