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. 2023 Jun 12;8(25):22623–22636. doi: 10.1021/acsomega.3c01034

Table 5. ADMET Properties of Top Two Selected Phytocompounds.

properties mulberrofuran M quercetin 3-(6″-caffeoylsophoroside)
Blood–Brain Barrier BBB+ BBB–
  0.5492 (0.7002)
Human Intestinal absorption HIA+ HIA+
  0.9651 (0.7179)
AMES toxicity non- AMES toxic AMES toxic
  0.8716 0.7010
carcinogens non-carcinogens non-carcinogens
  0.9281 0.9526
biodegradation not readily biodegradable not readily biodegradable
  0.9837 0.8433
acute oral toxicity III IV
  0.5666 0.4410
aqueous solubility (Logs) –3.6970 –2.6290