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. 2023 Jun 12;8(25):22623–22636. doi: 10.1021/acsomega.3c01034

Table 7. Effect of the Hydro-Methanolic Extract of C. hirsuta on Analysis of the Lipid Profile.

Sprague-Dawley rat Groups total cholesterol (mg/dL) triglycerides (mg/dL) HDL (mg/dL) LDL (mg/dL) VLDL (mg/dL)
normal control (NC) 75.3 ± 3.95 32.6 ± 7.35 41 ± 2.11 20 ± 4.65 27.3 ± 0.561
HFD-STZ (diabetic control) 187 ± 1.13*** 168 ± 6.88*** 25.4 ± 1.23*** 112 ± 13.8*** 34.4 ± 0.939***
HFD-STD (positive control) 81.8 ± 1.27*### 42.3 ± 1.67* 38.8 ± 1.02ns### 37.9 ± 0.464**### 24.2 ± 0.543***###
HFD-STZ 500 mg/kg 109 ± 4.88***### 44.7 ± 0.924**### 36.5 ± 0.91***### 39.8 ± 0.839***### 26.2 ± 0.415###
HFD-STZ 250 mg/kg 116 ± 1.29***### 46.5 ± 0.68***### 32.8 ± 0.615***### 46.6 ± 1.7***### 30 ± 0.716***###
HFD-STZ 125 mg/kg 119 ± 1.03***### 47.6 ± 0.899***### 29.1 ± 1.22***## 49.7 ± 0.941***### 32.6 ± 0.573***###