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. 2023 Jun 29;18:168. doi: 10.1186/s13023-023-02777-4

Table 2.

Factors associated with poorest EQ-5D-5L index value

Overall = 255
n (%) or mean (± SD)
Estimate (95% CI) p value Adjusted estimate (95% CI) p value
Gender [Male] 137 (53.3%) 0.07 (0.002 to 0.1) 0.04 0.02 (−0.03 to 0.07) 0.5
Age at evaluation (years) 39.3 ± 12.6 −0.003 (−0.006 to −0.00002) 0.04 −0.001 (−0.003 to 0.0007) 0.2
Disease duration (years) 19.6 ± 12.2 −0.001 (−0.004 to 0.002) 0.4
Hepatoneurological form 101 (39.3%) −0.3 (−0.3 to −0.2) < 0.001 −0.2 (−0.2 to −0.1) < 0.001
Presymptomatic form 3 (1.2%) −0.2 (−0.5 to 0.1) 0.3 −0.2 (−0.4 to 0.007) 0.06
Total BDI (/63) 7.4 ± 9.4 −0.02 (−0.02 to −0.02) < 0.001 −0.02 (−0.02 to −0.02) < 0.001

Bold value correspond to a statistically significant result

The following variables were included in the multivariate analysis: gender, age at evaluation, hepatoneurological form, presymptomatic form and total BDI

BDI Beck Depression Inventory