Table 1.
Demographic data and studied comorbidities of dermatitis herpetiformis (DH) and coeliac disease patients and their matched references.
| DH |
Coeliac disease |
|||
|---|---|---|---|---|
| Patients | References | Patients | References | |
| Total, n | 368 | 1099 | 1072 | 3197 |
| Females, n (%) | 180 (49) | 539 (49) | 729 (68) | 2174 (68) |
| Age at time of DH or coeliac disease diagnosis, median (IQR), years | 39 (5–84) | 39 (5–84) | 39 (0–85) | 39 (0–85) |
| Age at time of DH or coeliac disease diagnosis, n (%) | ||||
| Under 18 years | 18 (5) | 53 (5) | 232 (22) | 691 (22) |
| 18–40 years | 173 (47) | 517 (47) | 338 (32) | 1005 (32) |
| Over 40 years | 177 (48) | 529 (48) | 502 (47) | 1501 (47) |
| Year of DH or coeliac disease diagnosis, n (%) | ||||
| Before 1980 | 87 (24) | 259 (24) | 110 (10) | 329 (10) |
| Between 1981 and 1990 | 187 (51) | 559 (51) | 441 (41) | 1314 (41) |
| Between 1991 and 2001 | 94 (26) | 281 (26) | 521 (49) | 1554 (49) |
| Person-years of follow-up | 14 883 | 43 197 | 42 289 | 129 013 |
| Follow-up time, median (IQR), years | 46 (43–46) | 46 (39–46) | 46 (39–46) | 46 (39–46) |
| Age at end of follow-up, median (IQR), years | 68 (23–96) | 67 (17–101) | 62 (9–97) | 62 (6–100) |
| Comorbidities, n (%) | ||||
| Diabetes mellitus | 29 (8)a | 132 (12) | 115 (11)a | 248 (8) |
| Hypertension | 69 (19) | 239 (22) | 186 (17) | 508 (16) |
| Atrial fibrillation | 47 (13) | 147 (13) | 120 (11)a | 285 (9) |
| Hypercholesterolemia | 12 (3) | 53 (5) | 38 (4) | 88 (3) |
| Sleep apnoea | 16 (4) | 60 (6) | 32 (3) | 108 (3) |
| COPD | 3 (1) | 8 (1) | 7 (1) | 16 (1) |
IQR: interquartile range; COPD: chronic obstructive pulmonary disease.
aStatistically significant difference when compared to references.