TABLE 1.

Changes in the viral genome and proteins of ICV derived from the nasal washes of the huICV infected guinea pig (5 dpi) compared to inoculum^a

Segment	hICV inoculum Vs nasal wash
	Position	Nucleotide substitutions	Position	Amino acid substitutions
P3	1544	G-A	508	E-K
	1751	A-C	577	T-P
	1801	G-C	592	V-L
HEF	567	G-A	182	A-T
	1336	C-A
	1528	G-A	502	R-K
	1532	T-C
M	295	A-G	90	E-G
	391	T-A	122	M-K

^aNo mutations observed in PB2, PB1, NP, and NS segments.