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. 2023 May 18;97(6):e00635-23. doi: 10.1128/jvi.00635-23

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Copyright © 2023 Jiang et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International license.

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FIG 5 — Structure prediction for the 3′ UTR suggests a presence of conserved structural elements. Predicted RNA secondary structure for CoV-2-s2m-WT using SHAPE-MaP (A) and DMS-MaPseq (B) reactivity profiles. Predicted RNA secondary structure for CoV-2-s2m^Δ2–42 using SHAPE-MaP (C) and DMS-MaPseq (D) reactivity profiles. Each nucleotide is colored by its normalized reactivity. BSL, bulged stem-loop; SL1, stem-loop 1; HVR, hypervariable region; ONM, octanucleotide motif. Blue lines indicate the pseudoknot region.