TABLE 2.
Effects of physical exercise on circulating extracellular vesicles in rodents.
| Study | Sample | Physical exercise | Extracellular vesicles |
|---|---|---|---|
| Barcellos et al. (2020) | Male Wistar rats (2- and 22-month-old) | Forced treadmill running at 60% of VO2max, Climbing ladder of 85° inclination, and acrobatic exercise, combined. (6 min of aerobic training, 6 min of acrobatic training and 6 min of resistance training) | ⇑ BDNF, IL-1β, CD63 in EVs only from aerobic exercise aged rats. ß IL-1β in EVs from acrobatic and combined exercise adult rats |
| Duration: 20 min x 3x/week x 12 weeks | |||
| Type: Aerobic, Resistance, Acrobatic | |||
| Ma et al. (2018) | Male C57BL/6J mice (8–10-week-old) | Forced treadmill training at low intensity at 5 m.min-1 or moderate intensity at 10 m min-1 for 60 min/d, 5 days/week | ⇑ 2-fold, and 4-fold increase in endothelial progenitor derived exosomes in low intensity and moderate intensity exercise |
| Duration: 60 min/d x 5 days/week x 4 weeks | |||
| Type: Aerobic | |||
| Bertoldi et al. (2018) | Male Wistar rats (3-, 21-, and 26-month-old) | Moderate aerobic forced treadmill exercise | ⇑ 10% CD63 levels 18 h Post-Exercise |
| Duration: 20 min/day x 2 weeks | |||
| Type: Aerobic | |||
| Bei et al. (2017) | Male C57BL/6J mice (8-week-old) | Swimming (Day 1: 5 min twice a day, increase by 10 per day until 90 min) | ⇑ 1.85-fold NTA in serum EVs |
| Duration: Incremental until 90 min, 2x/day x 3 weeks | |||
| Type: Aerobic | |||
| Castaño et al. (2020) | Male C57BL/6J mice (15-week-old) | High intensity interval training (incremental until exhaustion) | ⇑ miR-133a, miR-133b, and miR-206 in circulating exosomes |
| Duration: 5 weeks | |||
| Type: Anaerobic |