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| HPV+ | HPV− | |
|---|---|---|
| Age | Younger patients | Older patients |
| Sex | More frequent in men | Frequent in men |
| Sexual behavior | Oral sex, high number of sexual partners | Variable |
| Primary tumor and metastasis | Small primary tumors in contrast to large metastases | Variable |
| Alcohol and tobacco | Frequent patients who do not smoke or drink | Frequent patients who smoke or drink |
| Prognosis | Better survival outcomes and better response to treatment |
Worse |
