Table 5.

Association between arousal index, nocturnal hypoxemia and carotid atherosclerosis

	Arousal Index* Beta (SD)	P-value	% time spent in SaO2* < 90% Beta (SD)	p-value
Vascular inflammation (Avg. TBRmean)
Model 1	0.0336 (0.0428)	0.43	−0.0009 (0.0184)	0.96
Model 2	0.0121 (0.0432)	0.78	−0.0065 (0.0178)	0.72
Model 3	0.0414 (0.0432)	0.34	−0.0012 (0.0214)	0.95
Vascular inflammation (Avg. TBRmax)
Model 1	0.0200 (0.0530)	0.71	0.0040 (0.0230)	0.86
Model 2	0.0049 (0.0525)	0.93	−0.0062 (0.0219)	0.78
Model 3	0.0377 (0.0523)	0.47	−0.0018 (0.0258)	0.94
Avg. Carotid wall thickness
Model 1	0.0090 (0.0353)	0.80	0.0239 (0.0135)	0.08
Model 2	0.0117 (0.0336)	0.73	0.0163 (0.0125)	0.19
Model 3	0.0280 (0.0343)	0.41	0.0266 (0.0152)	0.08

Model 1: Unadjusted

Model 2: Adjusted for age, sex, race/ethnicity

Model 3: Adjusted for Model 2 + BMI, smoking, hypertension, dyslipidemia

TBR target-to-background ratio, SaO2 oxygen saturation, SD standard deviation

^*Continuous Arousal index and percent time spent in SaO2 < 90% was log transformed due to skewness