Table 2. Lymphocytes subsets in pregnant women and in the Brazilian female adult healthy population.
| 2nd trimester (n = 49) | 3rd trimester (n = 30) | Women control (n = 30) | 2nd trimester x controls (p-value) |
3rd trimester x controls (p-value) |
||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cell subsets | (%) | (×103/µl) | (%) | (×103/µl) | (%) | (×103/µl) | (%) | (×103/µl) | (%) | (×103/µl) |
|
T CD3+
Median
[IQR]* [P10–P90]** |
76.50 [70.4–78.6] [66.5–83.2] |
1,320 [980–1,502] [758–2,372] |
76.30 [71.5–79.6] [58.2–83.2] |
1,282 [830–1,593] [634–1,691] |
73 70.5–77.5 70.1–81 |
1386 1164–1820 982–2160 |
0.38 | 0.30 | 0.34 | 0.10 0.10 |
|
T CD4+
Median
[IQR]* [P10–P90]** |
59 [55–64] [50–69] |
805 [619–1,043] [467–1,581] |
57 [52–62] [48–67] |
746 [537–877] [386–933] |
50 42–55 38–64 |
902 645–1128 547–1326 |
0.0001* | 0.63 | 0.01* | 0.08 |
|
T CD8+
Median
[IQR]* [P10–P90]** |
31 [27–39] [18–42] |
433 [303–538] [248–930] |
36 [30–39] [26–44] |
425 [290–616.2] [207–717] |
24 18–31.3 17–37 |
449 312–567 237–725 |
0.001* | 0.88 | 0.0004* | 0.94 |
|
B cell
Median
[IQR]* [P10–P90]** |
10 [8.6–13.4] [5.1–16.4] |
174↓
[121–240] [78–240]↓ |
9.5↓
[7.7–13.0] [5.0–16.0] |
160↓↓
[120–215] [55–312]↓ |
13 10–15 8–18 |
296 203–358 133–493 |
0.02* | 0.002* | 0.003* | 0.001* |
|
NK cell
Median
[IQR]* [P10–P90]** |
7 [4.8–10.5] [3.8–13.8] |
134↓
[72–210] [59–300]↓ |
6.8↓
[3.8–8.3] [2.4–19] |
100↓↓
[61–140] [45–189]↓↓ |
9.5 6–12 5–14 |
183 139–237 99–331 |
0.04 | 0.0004* | 0.02 | 0.019* |
Data are expressed as median; *IQR = interquartile range; **percentiles P10th–P90th; ↓= low levels; p > 0.05 in the analysis between; ## 2.5%–97.5% percentiles.