Table 1. Medical causes of Genito-Pelvic Pain/Penetration Disorder.

Superficial pain	Deep pain
Allergic reaction (e.g., latex)	Chronic pelvic pain syndrome
Congenital abnormalities (imperforate hymen, vaginal agenesis, vaginal septum)*	Crohn disease
Dermatologic diseases (lichen planus, lichen sclerosus)	Endometriosis
Fistula*	Hemorrhoids
Gynecological neoplasm*	Irritable bowel syndrome
Interstitial cystitis*	Neuropathies
Mechanical or chemical irritation	Pelvic floor muscle dysfunction
Pelvic organ prolapse*	Inflammatory pelvic disease
Perineal trauma*	Vaginitis
Pudendal nerve neuralgia*
Infections (herpes, HPV, vaginosis)
Atrophic vaginitis*
Inadequate lubrication (arousal difficulties, estrogen deficit)*

Source: Adapted from Bornstein et al.6

Note: *Conditions in which pain can be either superficial or deep.