Table 2. Characteristics of controlled ovarian stimulation (COS) and parameters related to ovarian response.
| Group 1 TSH < 2.5 mIU/L |
Group 2 TSH 2.5–4.0 mIU/L |
Group 3 TSH 4.0–10 mIU/L |
||
|---|---|---|---|---|
| (n = 455) | (n = 162) | (n = 33) | p | |
| COS protocol | 0.77 | |||
| Antagonist, n (%) | 292 (64.2) | 108 (66.7) | 21 (63.6) | |
| Agonist, n (%) | 100 (22) | 32 (19.8) | 9 (27.3) | |
| CC + Antagonist, n (%) | 63 (13.8) | 22 (13.6) | 3 (9.1) | |
| Total dose of FSH (IU) | 1650 (1,200–2,325) | 1,600 (1,213–2,225) | 1,427 (1,206–1,856) | 0.08 |
| Length of COS (days) | 9 (8–11) | 9 (8–11) | 9 (8–10.8) | 0.83 |
| Number of retrieved oocytes | 5 (3–10) | 6 (2–10) | 5 (3–9) | 0.88 |
| Number of mature oocytes (MII) | 4 (2–7) | 4 (2–7.5) | 3.5 (2–6) | 0.67 |
| Suspension due to poor response, n (%) | 19 (4.2) | 5 (3.1) | 2 (6.1) | 0.69 |
Abbreviations: CC, clomiphene citrate; COS, controlled ovarian stimulation; FSH, follicle-stimulating hormone; IU, international unities; MII, mature oocytes in metaphase II; TSH, thyroid-stimulating hormone.
Notes: Total dose of FSH, length of COS, suspension due to poor response, oocytes retrieved, and mature oocytes reported as median (interquartile range).
p determined either by Kruskal-Wallis or Chi-squared test.