Table 3. Frequency of the studied polymorphisms among different populations (endometriosis patients and controls).
| Polymorphism | Population | N* | Frequency among the controls (%) | Frequency among the cases (%) | Association with endometriosis | Reference |
|---|---|---|---|---|---|---|
| PGR +331 C > T (rs10895068) | PGR +331 T | |||||
| Estonia | 349 | 8.8 | 6.7 | No association | Lamp et al18 | |
| United States | 823 | 4.8 | 5.1 | No association | Trabert et al19 | |
| Netherlands | 165 | 9.7 | 2.3 | Protective (T allele) | van Kaam et al15 | |
| Brazil | 179 | 6.6 | 10.1 | No association | Present study | |
| CYP17A1 -34 A > G (rs743572) | CYP17A1 -34 G | |||||
| Turkey | 93 | 30.8 | 57.6 | No association | Bozdag et al17 | |
| China | 247 | 60.2 | 50.8 | Risk (A allele) | Hsieh et al11 | |
| China | 227 | 62.9 | 50.8 | Risk (A allele) | Hsieh et al12 | |
| China | 510 | 54.3 | 58.2 | No association | Juo et al13 | |
| Japan | 317 | 39.8 | 42.9 | No association | Kado et al10 | |
| United States | 823 | 39.3 | 34.8 | No association | Trabert et al19 | |
| Italy | 190 | 37.2 | 42.3 | No association | Vietri et al16 | |
| Brazil | 180 | 42.7 | 44.4 | No association | Present study | |
| CYP19A1 1531 G > A (rs10046) | CYP19A1 1531 A | |||||
| Korea | 412 | 55.9 | 55.8 | No association | Hur et al14 | |
| Estonia | 349 | 59.8 | 55.0 | No association | Lamp et al18 | |
| China | 371 | 56.4 | 57.5 | No association | Wang et al20 | |
| China | 202 | 41.0 | 35.3 | No association | Yang et al21 | |
| Brazil | 180 | 39.4 | 40.6 | No association | Present study | |
Abbreviations: CYP17A1, cytochrome P450 17A1; CYP19A1, cytochrome P450 19A1; PGR, progesterone receptor.
Note: *N total number of individuals included in the study (cases + controls).