Table 3. Association between drug use during pregnancy and specific severe maternal morbid conditions (hemorrhage, hypertension, other complication and NMCC).
| Drug use | With hemorrhage | Without hemorrhage | p-value | OR | 95% CI |
|---|---|---|---|---|---|
| Type of drug | n (%) | n (%) | |||
| No use | 44 (78.6) | 485 (83.3) | 0.34 | 1.0 | – |
| Tobacco | 10 (17.9) | 53 (9.1) | 0.04 | 2.17 | 1.03–4.54 |
| Alcohol | 6 (10.7) | 63 (10.8) | 0.97 | 0.98 | 0.40–2.39 |
| Cocaine | 2 (3.6) | 8 (1.4) | 0.22 | 2.65 | 0.55–12.8 |
| Any drug | 12 (21.4) | 96 (16.5) | 0.34 | 1.38 | 0.70–2.71 |
| With hypertension | Without hypertension | ||||
| Type of drug | n (%) | n (%) | p -value | OR | 95% CI |
| No use | 158 (83.6) | 371 (82.6) | 0.76 | 1.0 | – |
| Tobacco | 20 (10.6) | 43 (9.6) | 0.69 | 1.11 | 0.63–1.95 |
| Alcohol | 22 (11.6) | 47 (10.5) | 0.66 | 1.12 | 0.65–1.92 |
| Cocaine | 3 (1.6) | 7 (1.6) | 0.97 | 1.01 | 0.26–3.98 |
| Any drug | 31 (16,4) | 77 (17.1) | 0.81 | 0.94 | 0.60–1.49 |
| Type of drug | With another complication | Without another complication | p -value | OR | 95% CI |
| n (%) | n (%) | ||||
| No use | 86 (78.9) | 443 (83.7) | 0.22 | 1.0 | – |
| Tobacco | 15 (13.8) | 48 (9.1) | 0.13 | 1.59 | 0.86–2.97 |
| Alcohol | 12 (11) | 57 (10.8) | 0.94 | 1.02 | 0.53–1.98 |
| Cocaine | 5 (4.6) | 5 (0.9) | 0.01 | 5.00 | 1.43–17.7 |
| Any drug | 23 (21.1) | 85 (16.1) | 0.20 | 1.39 | 0.83–2.33 |
| Type of drug | With NMCC | Without NMCC | p -value | OR | 95% CI |
| n (%) | n (%) | ||||
| No use | 24 (72.7) | 505 (83.5) | 0.11 | 1.0 | – |
| Tobacco | 7 (21.2) | 56 (9.3) | 0.03 | 2.63 | 1.09–6.35 |
| Alcohol | 3 (9.1) | 66 (10.9) | 0.74 | 0.81 | 0.24–2.75 |
| Cocaine | 1 (3.0) | 9 (1.5) | 0.49 | 1.0 | – |
| Any drug | 9 (27.3) | 99 (16.4) | 0.10 | 1.91 | 0.86–4.24 |
Abbreviations: CI, confidence interval; NMCC, near miss clinical criteria; OR, odds ratio.