Table 7. Differentially expressed mRNA transcripts in vulvar melanoma relative to primary cutaneous melanoma.
| Gene | log2(fold change) | P-value | Gene | log2(fold change) | P-value | Gene | log2(fold change) | P-value | Gene | log2(fold change) | P-value |
|---|---|---|---|---|---|---|---|---|---|---|---|
| KRT17 | -3.2025 | 0.009008 | JUP | -1.4317 | 0.004237 | DLL3 | 2.6712 | 0.000567 | PLK1 | 1.1588 | 0.0001412 |
| CALML3 | -2.9585 | 0.006360 | SPINT1 | -1.4038 | 0.005632 | NUF2 | 1.5477 | 0.000544 | LMNB1 | 1.1467 | 0.0001629 |
| FGFR2 | -2.6768 | 7.06E-05 | MUC1 | -1.4034 | 0.008289 | AURKA | 1.5180 | 1.12E-06 | FEN1 | 1.1216 | 0.0057301 |
| TPSAB1/B2 | -2.6704 | 0.005842 | LOX | -1.3679 | 0.004187 | RFC3 | 1.5169 | 5.18E-06 | E2F1 | 1.1059 | 0.0025310 |
| SERPINB5 | -2.6176 | 0.004774 | FMOD | -1.3543 | 0.001216 | TOP2A | 1.5053 | 2.61E-05 | CDCA5 | 1.0979 | 0.0001875 |
| CCL19 | -2.5944 | 0.000219 | FZD4 | -1.3530 | 0.000615 | UBE2T | 1.4576 | 0.000113 | CACYBP | 1.0888 | 4.507E-05 |
| GPT | -2.2840 | 0.000139 | CMKLR1 | -1.3391 | 2.12E-05 | EXO1 | 1.4477 | 0.000360 | DTL | 1.0870 | 0.0036342 |
| ARG1 | -2.2429 | 0.002349 | PTCH2 | -1.2754 | 0.001810 | TPX2 | 1.4464 | 5.98E-06 | MCM4 | 1.0857 | 0.0016304 |
| LAMA2 | -2.2381 | 1.40E-05 | MAPK13 | -1.2603 | 0.004182 | EME1 | 1.4420 | 3.70E-05 | CCNB2 | 1.0682 | 0.0023296 |
| ESRP2 | -2.1375 | 0.002557 | NT5E | -1.2602 | 0.008887 | UBE2C | 1.3823 | 0.000120 | KIF2C | 1.0668 | 0.0001468 |
| PTGER3 | -2.1087 | 6.13E-05 | LAMC2 | -1.2579 | 0.005649 | BLM | 1.3731 | 4.42E-06 | KPNA2 | 1.0639 | 0.0002833 |
| TNS4 | -2.1065 | 0.001746 | PDGFRA | -1.2286 | 0.002290 | CDK1 | 1.3450 | 8.18E-05 | RRM2 | 1.0576 | 0.0001273 |
| HSD11B1 | -1.9241 | 0.000285 | CDKN1A | -1.1730 | 0.007485 | GTSE1 | 1.3443 | 1.95E-05 | CCNB1 | 1.0552 | 0.0012326 |
| HDC | -1.9233 | 0.001260 | LAMB3 | -1.1490 | 0.009884 | PCLAF | 1.3405 | 0.000103 | NME1 | 1.0463 | 0.0014547 |
| GRHL2 | -1.9112 | 0.002159 | CCR4 | -1.1431 | 0.001335 | BUB1 | 1.3199 | 8.37E-06 | CCNE1 | 1.0462 | 0.0037943 |
| CPA3 | -1.9107 | 0.002042 | PDCD1LG2 | -1.1372 | 0.001711 | CDC25A | 1.3112 | 0.000459 | BIRC5 | 1.0310 | 0.0010646 |
| ADH1A | -1.8655 | 0.003822 | IL15RA | -1.1103 | 0.001689 | TIMELESS | 1.2694 | 2.29E-05 | HJURP | 1.0181 | 0.0003849 |
| SPINT2 | -1.8501 | 0.000615 | CD40LG | -1.0809 | 0.003123 | BRIP1 | 1.2633 | 2.41E-05 | XRCC2 | 1.0150 | 0.0035612 |
| FBLN2 | -1.7157 | 0.000111 | PTGER4 | -1.0771 | 3.70E-04 | BUB1B | 1.2396 | 0.000180 | CLSPN | 1.0072 | 0.0003667 |
| EGFR | -1.6907 | 0.001269 | FLT3 | -1.0653 | 0.001132 | SMO | 1.2308 | 0.003742 | CHEK2 | 1.0061 | 0.0005617 |
| DCN | -1.6688 | 0.004306 | ITPR3 | -1.0249 | 0.005486 | KIF20A | 1.1993 | 0.000581 | |||
| GRB7 | -1.6020 | 0.004941 | JAG1 | -1.0145 | 0.008290 | AURKB | 1.1867 | 0.000346 | |||
| MS4A2 | -1.5596 | 0.007455 | AXL | -1.0113 | 0.005079 | BYSL | 1.1590 | 0.000378 |