Table 2. Top twenty genes with annotation upregulated from premetamorphosis (NF50) to metamorphic climax (NF62) in tadpole brain.
| Gene symbol | Gene title | ENSEMBL | Log2fold change* | Adjusted p value |
|---|---|---|---|---|
| dio3 | deiodinase, iodothyronine, type 3 | ENSXETG00000036613 | 3.275125254 | 2.94E-40 |
| avt | arginine vasotocin** | ENSXETG00000017979 | 2.328280168 | 1.28E-20 |
| thibz | thyroid hormone induced bZip protein | ENSXETG00000007922 | 2.296353968 | 1.19E-09 |
| spock2 | indolethylamine N-methyltransferase | ENSXETG00000026030 | 2.28515105 | 4.84E-12 |
| vstm5 | V-set and transmembrane domain containing 5 | ENSXETG00000017117 | 2.266298133 | 5.32E-29 |
| phf21a | BRAF35-HDAC complex protein BHC80 | ENSXETG00000011757 | 2.214433985 | 2.69E-32 |
| inhbb | inhibin subunit beta B | ENSXETG00000036045 | 2.200045605 | 1.99E-09 |
| pmepa1 | prostate transmembrane protein, androgen induced 1 | ENSXETG00000011263 | 2.195093687 | 1.46E-24 |
| apoe | apolipoprotein E | ENSXETG00000035511 | 2.127879577 | 8.93E-31 |
| dao | D-amino-acid oxidase | ENSXETG00000022308 | 2.112579694 | 3.37E-24 |
| cyp27a1 | cytochrome P450 family 27 subfamily A member 1 | ENSXETG00000025024 | 2.083714291 | 1.02E-08 |
| p2rx5 | purinergic receptor P2X, ligand gated ion channel, 5 | ENSXETG00000032944 | 1.98969067 | 2.89E-10 |
| cela1.2 | chymotrypsin like elastase 1, gene 2 | ENSXETG00000039717 | 1.976354459 | 2.54E-07 |
| nlrx1 | NLR family member X1 | ENSXETG00000021586 | 1.949234863 | 5.22E-36 |
| arhgap24 | Rho GTPase activating protein 24 | ENSXETG00000006200 | 1.887018231 | 7.6E-09 |
| bhlhe41 | basic helix-loop-helix family member e41 | ENSXETG00000023482 | 1.884565228 | 5.58E-17 |
| arhgap45 | Rho GTPase activating protein 45 | ENSXETG00000011260 | 1.877904 | 6.66E-22 |
| chrm2 | cholinergic eceptor muscarinic 2 | ENSXETG00000030443 | 1.877869602 | 1.87E-12 |
| sbf2 | zinc finger protein 816 | ENSXETG00000039440 | 1.825679583 | 4.21E-11 |
| trpm8 | transient receptor potential cation channel, subfamily M, member 8 | ENSXETG00000026873 | 1.824899962 | 3.94E-15 |
* Log2fold change of 1 = 2 fold increase.
** This gene is mislabeled in the genome database as arginine vasopressin (avp) which is a mammalian gene. The amphibian gene is arginine vasotocin (avt).