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. 2023 Jun 16;19(6):e1011232. doi: 10.1371/journal.pcbi.1011232

Table 1. Catalog of all simulations run and their corresponding command-line parameters.

Initial seed (-s) Baseline (-b) Initial state (-f)* Initial colony (-i)** [Tet.] in mM (-t) [Amp.] in mM (-a) Run time (-r)*** Start time (-n)
Baseline glucose simulations
0 Yes Default - 0 0 26002 0
100
10000
Tetracycline MIC simulations
0 No - 1 3.375E-03 0 14552 11550
100 2
10000 3
Tetracycline sensitivity simulations
0 No - 1 1.125E-03 0 14552 11550
2.25E-03
4.5E-03
9E-03
Tetracycline protein synthesis inhibition
0 No Default - 0 0 500 0
5E-05
1.08E-04
2.32E-04
5E-04
1.08E-03
2.32E-03
5E-03
1.08E-02
2.32E-02
5E-02
Ampicillin MIC simulations
0 No - 1 0 5.72E-03 14552 11550
100 2
10000 3
Ampicillin sensitivity simulations
0 No - 1 0 1.43E-03 14552 11550
2.86E-03
4.29E-03
1.145E-02

* Default refers to the file data/wcecoli_t0.json

** Each number refers to a saved snapshot from t = 11550 s of a glucose simulation: 1 = seed 0, 2 = seed 100, 3 = seed 10000. The seed of the saved snapshot was matched to the seed of the antibiotic sim.

*** Additional 2 seconds because no data is emitted after the last 2-second timestep.