Comparison 2. Cognitive rehabilitation versus inactive control at medium‐term follow‐up.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
2.1 Functional ability in targeted activities: personal goals ‐ performance (participant self‐report)	2	432	Std. Mean Difference (IV, Random, 95% CI)	1.46 [1.25, 1.68]
2.2 Functional ability in targeted activities: personal goals ‐ performance (informant report of participant)	3	446	Std. Mean Difference (IV, Random, 95% CI)	1.25 [0.78, 1.72]
2.3 Functional ability in targeted activities: personal goals ‐ satisfaction (participant self‐report)	2	432	Std. Mean Difference (IV, Random, 95% CI)	1.19 [0.73, 1.66]
2.4 General functional ability (informant report of participant)	3	380	Std. Mean Difference (IV, Random, 95% CI)	‐0.23 [‐0.43, ‐0.03]
2.5 Self‐efficacy (participant self‐report)	2	417	Mean Difference (IV, Random, 95% CI)	0.58 [‐0.05, 1.21]
2.6 Mood: anxiety (participant self‐report)	3	455	Mean Difference (IV, Random, 95% CI)	‐0.49 [‐1.56, 0.58]
2.7 Mood: depression (participant self‐report)	3	456	Mean Difference (IV, Random, 95% CI)	‐0.14 [‐0.49, 0.20]
2.8 Quality of life (participant self‐report)	5	783	Std. Mean Difference (IV, Random, 95% CI)	‐0.05 [‐0.32, 0.22]
2.9 Cognition: memory, global score	2	51	Std. Mean Difference (IV, Random, 95% CI)	‐0.43 [‐1.24, 0.38]
2.10 Cognition: memory, immediate recall	2	427	Mean Difference (IV, Random, 95% CI)	0.13 [‐0.12, 0.38]
2.11 Cognition: memory, delayed recall	2	426	Mean Difference (IV, Random, 95% CI)	0.66 [‐1.14, 2.46]
2.12 Cognition: sustained attention	2	413	Mean Difference (IV, Random, 95% CI)	0.43 [‐0.64, 1.49]
2.13 Cognition: auditory selective attention/working memory	2	386	Mean Difference (IV, Random, 95% CI)	0.47 [0.09, 0.84]
2.14 Cognition: verbal letter fluency	2	425	Std. Mean Difference (IV, Random, 95% CI)	‐0.03 [‐0.69, 0.63]
2.15 Quality of life: overall (care partner self‐report)	2	422	Mean Difference (IV, Random, 95% CI)	10.47 [‐5.97, 26.91]
2.16 Quality of life: physical health (care partner self‐report)	3	439	Mean Difference (IV, Random, 95% CI)	0.21 [‐0.15, 0.56]
2.17 Quality of life: psychological (care partner self‐report)	3	437	Mean Difference (IV, Random, 95% CI)	0.40 [‐0.24, 1.05]
2.18 Quality of life: social (care partner self‐report)	3	436	Mean Difference (IV, Random, 95% CI)	0.43 [0.11, 0.76]
2.19 Quality of life: environmental (care partner self‐report)	3	438	Mean Difference (IV, Random, 95% CI)	0.92 [‐0.66, 2.50]
2.20 Mood: anxiety (informant self‐report)	2	28	Mean Difference (IV, Random, 95% CI)	1.25 [‐3.52, 6.01]
2.21 Mood: depression (informant self‐report)	2	30	Mean Difference (IV, Random, 95% CI)	0.31 [‐3.07, 3.69]
2.22 Psychological wellbeing (care partner self‐report)	2	358	Mean Difference (IV, Random, 95% CI)	‐0.01 [‐0.69, 0.67]
2.23 Stress (care partner self‐report)	3	440	Mean Difference (IV, Random, 95% CI)	4.60 [‐2.39, 11.59]
2.24 Burden (care partner self‐report)	2	360	Std. Mean Difference (IV, Random, 95% CI)	‐0.10 [‐0.31, 0.10]