Table 2. Results of days of isolation and average cycle threshold values of samples according to results of culture in study of MPXV detection and isolation, Spain* .
| Cell | No. positive cultures | Mean days of positivity +SD (range) [95% CI] | Mean Ct of positive cultures +SD (range) [95% CI] | No. negative cultures | Mean Ct of negative cultures +SD (range) [95% CI] | p value |
|---|---|---|---|---|---|---|
| MRC-5 cells |
12 |
5.8 +2.4 (3–10)† [4.2–7.4] |
22.4 +6.4 (15–34) [18.3–26.5] |
9 |
29.5 +3.1 (25–34) [27.1–31] |
0.0068 |
| VeroE6 cells |
16 |
3.7 +1.3 (3–7)† [2.9–4.5] |
23.4 +5.8 (15–34) [20.3–26.4] |
5 |
32.02 +1.1 (31–34) [30.8–33.5] |
0.0035 |
| Both lines | 17 | 3.7 +1.3 (3–7) [2.9–4.5] | 23.9 +5.9 (15–34) [20.8–26.9] | 4 | 32.25 +1.25 (31–34) [30.2–34.2] | 0.0099 |
*Ct, cycle threshold; MPXV, monkeypox virus. †p = 0.012.