Table 1:
Baseline characteristics.
| All (N = 166a) | ID (N = 107) | Non-ID (N = 50) | |
|---|---|---|---|
| Demographics and lifestyle parameters | |||
| Age, years | 57 (45–65) | 56 (45–64) | 59 (47–66) |
| Men, n (%) | 98 (59) | 57 (53) | 37 (74) |
| Educational level, n (%) | |||
| Primary or secondary education not completed | 10 (6) | 6 (6) | 3 (6) |
| Finished low or intermediate level secondary education | 102 (61) | 75 (68) | 26 (52) |
| Finished high level secondary education or university degree | 54 (33) | 28 (26) | 21 (42) |
| Alcohol intake, units/week, n (%) | |||
| None | 62 (38) | 42 (40) | 17 (35) |
| 0–7 units per week | 60 (37) | 42 (40) | 15 (31) |
| >7 units per week | 41 (25) | 22 (21) | 16 (33) |
| Smoking, n (%) | 17 (11) | 11 (11) | 4 (9) |
| Clinical parameters | |||
| BMI, kg/m2 | 27.1 ± 4.1 | 27.0 ± 4.1 | 27.1 ± 4.1 |
| Systolic blood pressure, mmHg | 136 ± 16 | 135 ± 16 | 136 ± 17 |
| History of cardiovascular disease | 45 (27) | 30 (28) | 11 (22) |
| CIS Fatigue score | 60 (43–83) | 67 (43–86) | 54 (44–66) |
| Transplantation parameters | |||
| Time since transplantation, years | 5.8 (1.0–12.0) | 5.0 (1.0–11.3) | 10.0 (2.6–12.3) |
| Pre-emptive transplantation, n (%) | 58 (35) | 45 (42) | 12 (24) |
| Type of donor | |||
| Living, n (%) | 86 (52) | 60 (56) | 21 (42) |
| Postmortal, n (%) | 80 (48) | 47 (44) | 29 (58) |
| Laboratory parameters | |||
| eGFR mL/min/1.73 m2 | 51 ± 18 | 50 ± 17 | 52 ± 21 |
| Hemoglobin, g/dL | 13.5 ± 1.8 | 13.5 ± 1.9 | 13.4 ± 1.8 |
| MCV, fL | 90 ± 5 | 88 ± 5 | 92 ± 5 |
| Plasma ferritin, µg/L | 87 (37–170) | 44 (28–85) | 223 (143–333) |
| Transferrin saturation | 23.1 ± 9.7 | 19.7 ± 9.1 | 30.0 ± 6.8 |
| hs-CRP, mg/L | 1.9 (0.7–4.0) | 1.9 (0.7–3.9) | 2.2 (0.8–4.9) |
| Total cholesterol, mg/dL | 179 ± 41 | 181 ± 39 | 170 ± 40 |
| Medication use, n (%) | |||
| Calcineurin inhibitor | 125 (75) | 88 (82) | 31 (62) |
| Antiproliferative agent | 147 (89) | 93 (87) | 46 (92) |
| Prednisolone | 162 (98) | 105 (98) | 48 (96) |
| Benzodiazepines | 14 (9) | 10 (9) | 4 (8) |
| Antipsychotic agents | 1 (1) | 0 (0) | 1 (2) |
| Erythropoetin-stimulating agents | 3 (2) | 2 (1) | 1 (2) |
Data are presented as mean ± SD, median (IQR) or number (n) with percentage (%).
aIn nine patients, TSAT was missing and therefore it was unknown whether they had ID.
TSAT was available for 151 KTRs. Data on smoking status were available for 155 KTRs. CIS Fatigue score was available in 153 KTRs.
MCV, mean corpuscular volume.