Table 3.
Localization, procedures, and postoperative complications in benign insulinoma
| Total cohort (n = 57) |
Group 1 (n = 36) |
Group 2 (n = 21) |
P value# | |
|---|---|---|---|---|
| Localization inside pancreas | ||||
| Head | 26 (45.6%) | 19 (52.8%) | 7 (33.3%) | 0.179b |
| Body/tail | 31 (54.4%) | 17 (47.2%) | 14 (66.7%) | |
| Surgical access | ||||
| Conventional | 39 (68.4%) | 29 (80.6%) | 10 (47.6%) | 0.017b |
| MIS | 18 (31.6%) | 7 (19.4%) | 11 (52.4%) | |
| MIS, if localization in head | 2/26 (7.7%) | 1/19 (5.3%) | 1/7 (14.3%) | 0.474b |
| MIS, if localization in body/tail | 16/31 (51.6%) | 6/17 (35.3%) | 10/14 (71.4%) | 0.073b |
| Surgical procedures | ||||
| Enucleation | 31 (54.4%) | 20 (55.6%) | 11 (52.4%) | 1.000b |
| DPR | 13 (22.8%) | 8 (22.2%) | 5 (23.8%) | 1.000b |
| PPD | 8 (14.0%) | 6 (16.7%) | 2 (9.5%) | 0.679b |
| Enuc. + DPR additional | 5 (8.8%) | 2 (5.6%) | 3 (14.3%) | 0.346b |
| Intraoperative ultrasound | 56 (98.2%) | 35 (97.2%) | 21 (100%) | 1.000b |
| Complications | ||||
| Clavien-Dindo ≥ 3 | 14 (24.6%) | 9 (25.0%) | 5 (23.8%) | 1.000b |
|
POPF grade B POPF grade C |
5 (8.8%) 2 (3.5%) |
2 (5.6%) 1 (2.8%) |
3 (14.3%) 1 (4.8%) |
0.346b 1.000b |
| Non-surgical complications (LAE etc.) | 5 (8.8%) | 4 (11.1%) | 1 (4.8%) | 0.642b |
| Reoperation due to bleeding | 6 (10.5%) | 4 (11.1%) | 2 (9.5%) | 1.000b |
| Intraabdominal abscess | 9 (15.8%) | 5 (13.9%) | 4 (19.0%) | 0.712b |
#P value was calculated between groups 1 and 2
MIS minimally invasive surgery, Enuc enucleation, DPR distal pancreatic resection, PPD partial pancreaticoduodenectomy, POPF postoperative pancreatic fistula, LAE pulmonary embolism
aMann-Whitney U test
bFisher’s exact test