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. 2023 Jan 31;44(7):1366–1379. doi: 10.1038/s41401-023-01057-y

Fig. 5. The protective effects of NG-R1 involve JNK/p38 signaling.

Fig. 5

a Representative immunofluorescence images showing TUNEL (red) staining in the infarct border zone in the various groups. Scale bar = 200 µm. b Quantitative analysis of a. c Representative images of M-mode echocardiography in each group. d Quantitative echocardiographic analysis of LVEF and LVFS. e, f Representative images of Masson trichrome-stained MI/R hearts and quantification of the fibrosis area (%). Scale bar = 100 µm. g Quantitative reverse transcription polymerase chain reaction analysis of α-SMA, collagen I and fibronectin. The data are represented as the mean ± SEM (n = 6 for each group). **P < 0.01 vs. the Sham group. #P < 0.05 and ##P < 0.01 vs. the MI/R group. $P < 0.05 and $$P < 0.01 vs. the MI/R + NG-R1 group.