Table 1.
Demographics and Baseline Clinical Characteristics of the Subjects
| Extended cohort including all eyes (Unlimited follow-up) | Stable eye cohort (Max follow-up = 1.5 years) | |
|---|---|---|
|
| ||
| Characteristic | n = 230 eyes (150 subjects) | n = 86 eyes (62 subjects) |
|
| ||
| Age (years) | 67.7 (65.8, 69.6) | 65.2 (62.0, 68.5) |
|
| ||
| Sex (Female/ Male) | 80/70 | 37/25 |
|
| ||
| Race (African American/ non-African American) | 39/111 | 19/43 |
|
| ||
| Self-reported hypertension, n(%) | 87 (58%) | 32 (52%) |
|
| ||
| Self-reported diabetes, n(%) | 22 (15%) | 9 (15%) |
|
| ||
| Eye related variables | ||
|
| ||
| Diagnosis (%) | ||
| Healthy | 28 (12%) | 18 (21%) |
| Glaucoma suspect | 65 (28%) | 28 (33%) |
| POAG | 137 (60%) | 40 (47%) |
|
| ||
| Mean IOP during follow up (mmHg) | 15.0 (14.4, 15.5) | 15.4 (14.5, 16.3) |
|
| ||
| Axial length (mm) | 24.4 (24.2, 24.5) | 24.5 (24.2, 24.7) |
|
| ||
| CCT (μm) | 541.1 (536, 546.3) | 538.6 (530.2, 547.1) |
|
| ||
| Baseline 24-2 VF MD (dB) | −3.0 (−3.6, −2.4) | −2.0 (−2.7, −1.3) |
|
| ||
| Baseline 24-2 VF PSD (dB) | 4.1 (3.6, 4.5) | 3.3 (2.7, 4.0) |
|
| ||
| Baseline wiGCC thickness (μm) | 92.2 (90.5, 93.9) | 94.5 (91.9, 97.0) |
|
| ||
| Baseline pfGCC thickness (μm) | 97.2 (95.3, 99.0) | 99.8 (97.0, 102.5) |
|
| ||
| Baseline wiVD (%) | 44.9 (44.3, 45.5) | 45.4 (44.5, 46.4) |
|
| ||
| Baseline pfVD (%) | 47.8 (47.1, 48.4) | 48.3 (47.3, 49.3) |
|
| ||
| OCT/OCTA SSI | 67.7 (66.8, 68.7) | 68.7 (67.1, 70.2) |
|
| ||
| Follow-up duration (years) | 3.0 (2.8, 3.2) | 1.2 (1.1, 1.2) |
|
| ||
| Number of follow-up visits | 5.1 (4.9, 5.3) | 4.3 (3.8, 4.8) |
*
Values are shown in mean (95% confidence interval), unless otherwise indicated.
Abbreviations: CCT = central corneal thickness; IOP = intraocular pressure; MD = mean deviation; OCT = optical coherence tomography; OCTA = optical coherence tomography angiography; pfGCC =parafoveal ganglion cell complex; pfVD = parafoveal vessel density; POAG = primary open angle glaucoma; PSD = pattern standard deviation; SSI = signal strength index; VF = visual field; wiGCC = whole-image ganglion cell complex; wiVD = whole-image vessel density