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. 2023 Jan 7;47(4):543–551. doi: 10.1016/j.jgr.2023.01.002

Fig. 2.

Fig. 2

The effect of PPD on TGF-β1 and AMPK signaling pathways in lung tissue of mice with BLM-induced pulmonary fibrosis. (A&B) TGF-β1 protein and mRNA levels. (C) p-Smad2 protein expression. (D-G) Col Ⅰ and α-SMA protein and mRNA levels. (H–K) E-cadherin, Vimentin, p-AMPK and SIRT1 protein expression. Protein was detected in lung tissues by Western blotting and mRNA levels by qRT-PCR, and data are shown as mean ± S.D. (n = 4). ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001.