Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 May 28;10(4):1279–1290. doi: 10.1016/j.gendis.2022.05.014

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2022 The Authors. Publishing services by Elsevier B.V. on behalf of KeAi Communications Co., Ltd.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

PMC Copyright notice

Fig. 1 — Proposed regulatory mechanism of clock genes in cancer. AC, adenyl cyclase; ACER2, alkaline ceramidase 2; ATG5, autophagy regulate gene 5; BC, breast cancer; CDK5, cyclin-dependent kinase 2; CSC, cancer stem cell; CRC, colorectal cancer; DOX, doxorubicin; EMT, epithelial–mesenchymal transition; GC, gastric cancer; G6PD, glucose-6-phosphate dehydrogenase; IL8, interleukin 8; ISO, isoproterenol; MDM2, mouse double minute 2; MMP2, matrix metalloproteinase-2; MMP9, matrix metalloproteinase-9; NPC, nasopharyngeal carcinoma; NSCLC, nonsmall cell lung cancer; MRP2, ATP binding cassette subfamily C member 2; OV, ovarian cancer; OSCC, oral squamous cell carcinoma; PFKFB3, 6-phosphofructokinase-2/fructose-2,6-bisphosphatase; P-gp, P-glycoprotein; PPP, pentose phosphate pathway; SP1, specific protein 1; S1P, sphingosine 1-phosphate; TNBC, triple-negative breast cancer; TNFα, tumor necrosis factorα; u-PA, urokinase-type plasminogen activator; VEGF, vascular endothelial growth factor.