Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 15;14:1193015. doi: 10.3389/fneur.2023.1193015

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Brauchle, Rapp, Senel, Huss, Dreyhaupt, Klose, Süße, Stürner, Leypoldt, Tumani and Lewerenz.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Flowchart of the study profile. CSF: cerebrospinal fluid, OCB−/+: oligoclonal bands negative/positive, PSIIR−/+: polyspecific intrathecal immune response negative/positive, MS: multiple sclerosis. PSIIR definitely negative: patients seronegative for only one of the pathogens tested and all other CSF/serum antibody indices (AI) normal or no seronegativity for any pathogen tested when one AI was elevated. PSIIR reaction rated negative: the PSIIR reaction was rated negative due to infection-related AI elevation or plasmapheresis-induced CSF/plasma disequilibrium.