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RSV iSNV distributions along the viral genome. A #iSNV versus mean sequencing depth for each site over RSV genomes of patients. Dashed line shows the linear regression. B Total iSNV numbers (left panel) and sum of #iSNV/kb values (right panel) for RSV-B in the study along genomic regions and ORF regions. C, D Distribution of iSNVs at codon positions (C) and non-synonymous (N)/synonymous (S) iSNVs (D) of ORFs.
