Fig. 5. (A) Cell viability study employing 2D models of A549 cells after 48 h of treatment. (B) Calculated IC50 values (n = 3) for the different compounds. (C) Comparison of cell viability in 2D and 3D A549 cell cultures after 48 h of treatment with cisplatin, a Pt(iv) precursor, and NPs at a concentration of 100 μM of Pt (n = 3), *p < 0.04 and **p < 0.005.
