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. Author manuscript; available in PMC: 2024 Mar 1.
Published in final edited form as: Br J Pharmacol. 2022 Dec 5;180(5):667–680. doi: 10.1111/bph.15903

Figure 6: C781 has limited effect on acute A. alternata-induced airway epithelial mucin expression.

Figure 6:

Representative histochemical stain (PAS) micrographs of lung sections showed minimal epithelial mucin staining in (A) HBSS or (B) C781 control images with an increase in staining following (C) A. alternata exposure that appeared to be reduced in (D) A. alternata + C781 exposed animals. (E) Semi-quantitative scoring of PAS-stained lung sections showed significant increases from controls in the A. alternata (Alt) and A. alternata + C781- (Alt + C781) treated animals. (E) Semi-quantitative scoring of collapsible airways in PAS-stained sections showed significant increases from controls (HBSS or C781 alone) in the A. alternata treated animals that was significantly reduced in the presence of C781. Histochemistry were from 6 (HBSS, C781 and Alt) and 5 (Alt + C781) animals. Bar in D denotes 100 μm. * denotes significant difference between Alt and HBSS control; # denotes significant difference between Alt and Alt + C781; ^ denotes significant difference between Alt and C781 control.