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. 2023 Jun 15;17:1213732. doi: 10.3389/fncel.2023.1213732

FIGURE 2.

FIGURE 2

RSL3 does not alter membrane conductances of spiny neurons. (A) Sample traces of eletrotonic potentials and firing activity induced in layer IV spiny neurons (in the presence of AMPA, NMDA and GABA receptor antagonists), in the absence (black) or in the presence of RSL3 (5 μM, red), by hyperpolarizing an depolarizing current pulses, respectively. (B) Each point represents the mean firing rate of spiny neurons evoked by a depolarizing current step of 40 pA from a holding potential of –70 mV, in the absence (black, n = 6/3animals) or in the presence (red, n = 6/3animals) of RSL3 (5 μM). Bars represent SEM. Note complete overlapping of black and red points.