Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Regulation of the extracellular matrix in drug memory processing. A working hypothesis of ECM alterations from acute to chronic stages of substance use. In general, ECM molecules are degraded in acute stages, possibly to allow for formation of new synapses. PNNs and ECM molecules are generally increased with chronic use which may contribute to the strength of reward memories associated with SUD that confer relapse.
