Table 1.
Baseline characteristics of hepatitis B virus-acute on chronic liver failure patients
|
|
All patients (n = 330)
|
Survivor patients (n = 195)
|
Non-survivor patients (n = 135)
|
P value
|
| Age (yr) | 49.68 ± 12.39 | 47.91 ± 12.12 | 52.23 ± 12.39 | 0.002 |
| Male, n (%) | 277 (83.9) | 162 (83.1) | 115 (85.2) | 0.068 |
| Costs (dollars) | 10133.88 (5886.57-15955.07) | 10734.72 (5958.59-16913.77) | 9107.89 (5727.32-14945.14) | 0.065 |
| Ascites, n (%) | 0.016 | |||
| Mild | 158 (47.9) | 104 (53.3) | 54 (40.0) | |
| Medium | 102 (30.9) | 59 (30.3) | 43 (31.9) | |
| Severe | 70 (21.2) | 32 (16.4) | 38 (28.1) | |
| PLT (109/L) | 108.00 (72.75-144.25) | 115.00 (82.00-148.00) | 89.00 (57.00-138.00) | 0.004 |
| PT (s) | 22.70 (19.30-29.25) | 21.10 (18.90-25.20) | 25.40 (21.80-32.80) | < 0.001 |
| INR | 2.01 (1.74-2.64) | 1.88 (1.69-2.30) | 2.4 (1.94-3.07) | < 0.001 |
| Hemoglobin (g/L) | 122.00 (102.00-136.00) | 123.00 (107.00-137.00) | 121.00 (94.00-135.00) | 0.166 |
| Bilirubin (μmol/L) | 312.91 ± 135.85 | 299.15 ± 126.15 | 332.79 ± 146.96 | 0.027 |
| Albumin (g/L) | 31.40 (28.20-34.25) | 31.50 (28.20-34.60) | 31.10 (28.20-33.30) | 0.151 |
| Creatinine (μmol/L) | 66.60 (57.08-84.73) | 65.60 (57.00-81.00) | 68.30 (57.50-91.90) | 0.294 |
| BUN (mmol/L) | 4.00 (2.80-6.10) | 4.00 (2.80-5.50) | 4.10 (3.00-7.60) | 0.074 |
| Serum Na (mmol/L) | 137.00 (133.30-139.10) | 137.00 (133.20-139.00) | 136.90 (133.30-139.10) | 0.882 |
| LWR | 0.17 (0.11-0.23) | 0.19 (0.12-0.25) | 0.13 (0.08-0.20) | < 0.001 |
| CTPs | 11.00 (10.00-12.00) | 11.00 (10.00-12.00) | 12.00 (11.00-13.00) | < 0.001 |
| MELDs | 23.17 (20.03-27.27) | 21.59 (18.86-25.46) | 25.04 (21.78-29.10) | < 0.001 |
| COSSHACLFIIs | 7.18 (6.54-8.12) | 6.80 (6.30-7.37) | 7.95 (7.20-8.70) | < 0.001 |
PLT: Platelet; PT: Prothrombin time; INR: International normalized ratio; BUN: Blood urea nitrogen; LWR: Lymphocyte-to-white blood cell ratio; CTPs: Child-Turcotte-Pugh score; MELDs: Model for end-stage liver disease score; COSSHACLFIIs: Chinese group on the study of severe Hepatitis B-Acute-on-chronic liver failure II score.