Table 3.
Clinical characteristics between low and high lymphocyte-to-white blood cell ratio groups in hepatitis B virus-acute on chronic liver failure patients
|
|
Low LWR level (n = 77)
|
High LWR level (n = 253)
|
P value
|
| Age (yr) | 52.99 ± 12.57 | 48.67 ± 12.19 | 0.007 |
| Male, n (%) | 59 (76.6) | 218 (86.2) | 0.046 |
| Costs (dollars) | 7625.18 (3899.37-12070.55) | 10984.59 (6639.92-16693.10) | < 0.001 |
| Ascites, n (%) | 0.007 | ||
| Mild | 25 (32.5) | 133 (52.6) | |
| Medium | 29 (37.7) | 73 (28.9) | |
| Severe | 23 (29.9) | 47 (18.6) | |
| PLT (109/L) | 86.00 (55.50-138.50) | 110.00 (79.50-145.50) | 0.039 |
| PT (s) | 23.20 (19.70-33.50) | 22.40 (19.20-28.00) | 0.016 |
| INR | 2.13 (1.76-3.11) | 1.99 (1.73-2.54) | 0.018 |
| Hemoglobin (g/L) | 109.00 (89.50-125.50) | 125.00 (108.00-139.00) | < 0.001 |
| Bilirubin (μmol/L) | 331.52 ± 153.46 | 307.25 ± 129.82 | 0.170 |
| Albumin (g/L) | 30.10 (26.30-32.50) | 31.80 (28.85-34.55) | < 0.001 |
| Creatinine (μmol/L) | 82.40 (58.40-126.10) | 64.80 (56.85-77.95) | < 0.001 |
| BUN (mmol/L) | 7.00 (4.00-11.10) | 3.70 (2.70-5.20) | < 0.001 |
| Serum Na (mmol/L) | 135.30 (131.50-139.05) | 137.20 (133.90-139.10) | 0.086 |
| CTPs | 12.00 (11.00-13.00) | 11.00 (10.00-12.00) | < 0.001 |
| MELDs | 25.79 (22.52-30.91) | 22.44 (19.55-26.13) | < 0.001 |
| COSSHACLFIIs | 8.11 (7.26-9.06) | 6.94 (6.40-7.79) | < 0.001 |
| 28-d mortality, n (%) | 46 (59.7) | 89 (35.2) | < 0.001 |
PLT: Platelet; PT: Prothrombin time; INR: International normalized ratio; BUN: Blood urea nitrogen; LWR: Lymphocyte-to-white blood cell ratio; CTPs: Child-Turcotte-Pugh score; MELDs: Model for end-stage liver disease score; COSSHACLFIIs: Chinese group on the study of severe Hepatitis B-Acute-on-chronic liver failure II score.