Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 16;11:1208279. doi: 10.3389/fcell.2023.1208279

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2023 Petrelli, Oztürk, Pind, Ayele, Fainsod and Hicks.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Gsc ^+/Cyp26A1 mice have severe craniofacial malocclusions. Gsc ^+/Cyp26A1 mice (B) demonstrate a curvature in the pre-maxillary process when compared to WT littermates (A). Gsc ^+/Cyp26A1 mice (E), red arrow; (F), white arrow do not have a curvature of the mandibular component, the mandible is straight when compared to the skull as seen in WT littermates (C), red arrow; (D), white arrow. The curvature to the maxillary component can be seen to impact the natural grinding of the incisors, ultimately causing a severe malocclusion in Gsc ^+/Cyp26A1 mice (B, I = maxillary incisors); the incisors grind normally in WT littermate mice (A, I = maxillary incisors).