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Gsc+/Cyp26A1 E8.5 embryos show changes in RARE-LacZ expression, specifically in the developing frontonasal prominence.
| Embryo age | Genotype | Normal | Mild pattern/Expression change | Severe pattern/Expression change | p-value a |
|---|---|---|---|---|---|
| E8.5 | WT | 48 | 0 | 0 | p = 1.4 × 10−7 |
| Gsc:Cyp26A1 | 16 | 9 | 5 | ||
| E9.5 | WT | 9 | 0 | 0 | ns |
| Gsc:Cyp26A1 | 7 | 0 | 0 | ||
| E10.5 | WT | 8 | 0 | 0 | ns |
| Gsc:Cyp26A1 | 6 | 0 | 0 | ||
| E11.5 | WT | 8 | 0 | 0 | ns |
| Gsc:Cyp26A1 | 7 | 0 | 0 |
Fisher’s exact Test: ns, no statistically significant difference between groups.
