Table 4.

Heritability estimates from LDSC

Trait	Observed scale h2	SE	P-value	Liability scale h2
iPSYCH infection load (with covariate for overall psychiatric diagnosis)	0.0221	0.0055	2.93 × 10−5	–
iPSYCH infection load (without covariate for overall psychiatric diagnosis)	0.0252	0.0055	2.30 × 10−6	–
iPSYCH overall infection (with covariate for overall psychiatric diagnosis)	0.0157	0.0048	0.0005362	0.0242
iPSYCH overall infection (without covariate for overall psychiatric diagnosis)	0.0178	0.0048	0.0001043	0.0274
iPSYCH overall psychiatric diagnosis	0.0763	0.0061	3.37 × 10−36	0.0956
FinnGen infections (iPSYCH LD scores)	0.0118	0.0030	4.19 × 10−5	0.0210
FinnGen infections (European LD scores)	0.0159	0.0020	9.33 × 10−16	0.0283
FinnGen any mental disorder (iPSYCH LD scores)	0.0260	0.0019	6.31 × 10−43	0.0486
FinnGen any mental disorder (European LD scores)	0.0437	0.0028	3.25 × 10−55	0.0817

Note: The p-values are not corrected. ‘Liability scale h²’ is relevant only to binary traits; in all cases, the h² in the ‘observed scale h²’ column is the one reported by LDSC. SE, standard error.