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. 2023 May 18;151:e93. doi: 10.1017/S0950268823000687

Table 5.

Genetic correlation estimates from LDSC

Trait 1 Trait 2 rg SE P-value
iPSYCH overall infection iPSYCH overall psychiatric diagnosis 0.4061 0.1049 0.000108
iPSYCH overall infection FinnGen any mental disorder 0.4131 0.0956 1.55 × 10−5
iPSYCH overall infection FinnGen infections 0.6189 0.1394 9.01 × 10−6
iPSYCH overall psychiatric diagnosis FinnGen any mental disorder 0.6660 0.0444 7.34 × 10−51
iPSYCH overall psychiatric diagnosis FinnGen infections 0.4062 0.1118 0.000280
iPSYCH infection load iPSYCH overall psychiatric diagnosis 0.4298 0.0901 1.84 × 10−6
iPSYCH infection load FinnGen infections 0.6347 0.1279 6.96 × 10−7
iPSYCH infection load FinnGen any mental disorder 0.3388 0.0733 3.80 × 10−6
iPSYCH infection load iPSYCH overall infection 0.9837 0.0364 7.57 × 10−161
FinnGen infections (iPSYCH LD scores) FinnGen any mental disorder (iPSYCH LD scores) 0.5603 0.1110 4.47 × 10−7
FinnGen infections (European LD scores) FinnGen any mental disorder (European LD scores) 0.6465 0.0555 2.33 × 10−31

Note: When at least one of the traits was measured in iPSYCH, iPSYCH-generated LD scores were used. The p-values are not corrected. SE, standard error.