Fig. 6.

FMT from healthy volunteers improved the synaptic plasticity and glial activities induced by CRS in mouse brains. A, B Colocalization of F-actin and Drebrin along with the respective coefficient analysis. C, D Colocalization of Synapsin1 and PSD95 along with the respective coefficient analysis. E Protein expression of Drebrin, PSD95, and Syn1 along with their statistical graphs. F Protein expression of GFAP and Iba1 along with their statistical graphs. G, H MFI of GFAP and their statistical graphs. I, J MFI of Iba1 and their statistical graphs. Scale bar 50 μm. Data were displayed as mean ± SEM. Significant differences were determined via one-way ANOVA and Tukey’s multiple comparison procedure. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001 vs. the CTR group; ^#p < 0.05, ^##p < 0.01, ^###p < 0.001, ^####p < 0.0001 vs. the CRS group; ^&p < 0.05, ^&&p < 0.01, ^&&&p < 0.001 vs. the CRS + HC-tr group