Table 2.
Menopausal stage, menopausal symptoms and health-related quality of life in women resident in Harare, by HIV status
| Total (n = 378) |
HIV – (n = 193) |
HIV + (n = 185) |
p value * | |
|---|---|---|---|---|
| Menopausal stage, n (%) | ||||
| Pre-menopause | 173(45.8) | 94(48.7) | 79(42.7) | 0.278 |
| Peri-menopause | 51(13.5) | 28(14.5) | 23(12.4) | |
| Post menopause | 154(40.7) | 71(36.8) | 83(44.9) | |
| Total MRS symptoms, n (%) | ||||
| No, little (≤ 4) | 177(46.8) | 101(52.3) | 76(41.1) | 0.005 |
| Mild (5–8) | 97(25.7) | 52(26.9) | 45(24.3) | |
| Moderate (9–16) | 81(21.4) | 35(18.1) | 46(24.9) | |
| Severe (≥ 17) | 23(6.1) | 5(2.6) | 18(9.7) | |
| Somatic symptomsub-domain, n (%) | ||||
| No, little (0–2) | 190(50.3) | 102(52.9) | 88(47.6) | 0.250 |
| Mild (3–4) | 91(24.1) | 50(25.9) | 41(22.2) | |
| Moderate (5–8) | 82(21.7) | 35(18.1) | 47(25.4) | |
| Severe (≥ 9) | 15(4.0) | 6(3.1) | 9(4.9) | |
| Psychological symptomsub-domain, n (%) | ||||
| No, little (0–1) | 228(60.3) | 135(70.0) | 93(50.3) | < 0.001 |
| Mild (2–3) | 75(19.8) | 30(15.5) | 45(24.3) | |
| Moderate (4–6) | 53(14.0) | 26(13.5) | 27(14.6) | |
| Severe (≥ 7) | 22(5.8) | 2(1.0) | 20(10.8) | |
| Urogenital symptomsub-domain, n (%) | ||||
| No, little (0) | 172(45.5) | 100(51.8) | 72(38.9) | 0.009 |
| Mild (1) | 63(16.7) | 36(18.7) | 27(14.6) | |
| Moderate (2–3) | 88(23.3) | 35(18.1) | 53(28.7) | |
| Severe (≥ 4) | 55(14.5) | 22(11.4) | 33(17.8) | |
| HRQoL, mean (SD) | 26.4(3.5) | 26.5(3.3) | 26.3(3.7) | 0.642 |
Participants’ menopausal symptoms by HIV status. *p values generated using Chi-square tests of association for categorical variables and t-test for normally distributed continuous variables, MRS: Menopause Rating Scale, HRQoL: Health Related Quality of Life