TABLE 2.
Clusters of significant differences in cortical morphometry between TD and ASD.
| Measurement | Region | Size (mm2) | x | y | z | CWP | NV | Cohen’s d | 95% CI | |
| Thickness | ASD > TD | Left Rostral Anterior Cingulate | 1122.47 | –7.3 | 37.5 | 13.5 | 0.0001 | 2270 | 1.0775 | 0.5523, 1.6026 |
| Left Fusiform | 687.19 | –35.5 | –44.1 | –21.1 | 0.0035 | 1181 | 1.3755 | 0.831, 1.92 | ||
| Right Lingual | 1946.68 | 16.7 | –65.3 | –3.6 | 0.0001 | 2351 | 1.6948 | 1.1317, 2.2579 | ||
| Right Rostral Middle Frontal | 1005.30 | 20.0 | 50.4 | –13.4 | 0.0002 | 1625 | 0.9048 | 0.395, 1.416 | ||
| Right Lateral Occipital | 909.12 | 27.3 | –93.1 | 4.6 | 0.0006 | 1154 | 0.7224 | 0.2208, 1.224 | ||
| Right Insula | 715.56 | 37.5 | –2.7 | 1.6 | 0.0036 | 1892 | 1.3368 | 0.8012, 1.8724 | ||
| Area | ASD < TD | left Paracentral | 973.87 | –17.1 | –30.1 | 43.1 | 0.0015 | 2670 | 1.1769 | 0.6432, 1.7106 |
| Right Rostral Middle Frontal | 1332.19 | 27.7 | 57.8 | –9.5 | 0.0001 | 1849 | 0.9599 | 0.4388, 1.481 | ||
Results from whole-brain analysis of cortical metrics between ASD and TD peers, controlling for age, gender, and total cortical volume (corrected for multiple comparisons using Monte Carlo stimulations p < 0.005). CWP, Cluster-Wise P-value; NV, number of vertices; CI, confidence intervals.