Table 2:
Microbiology data in neonates with necrotizing enterocolitis
| Total Cohort | Medical NEC | Surgical NEC | Short Bowel Present | Short Bowel Absent | |
|---|---|---|---|---|---|
| n = 50 | n = 17 | n = 33 | n = 20 | n = 13 | |
| Monomicrobial, n (%) | 41 (82) | 17 (100.0) | 24 (72) | 13 (65) | 11 (84.6) |
| * Polymicrobial, n (%) | 9 (18) | 0 | 9 (28) | 7 (35) | 2 (15.3) |
| Gram Negative, n (%) | 22 (44) | 7 (41.2) | 15 (45) | 12 (60) | 4 (30.6) |
| Klebsiella pneumoniae, n (%) | 8 (16) | 2 (11.8) | 6 (18) | 4 (20) | 2 (15.3) |
| Escherichia coli, n (%) | 6 (12) | 1 (5.9) | 5 (15) | 3 (15) | 2 (15.3) |
| Serratia marcescens, n (%) | 4 (8) | 2 (11.8) | 2 (6) | 2 (10) | 0 |
| Enterobacter cloacae, n (%) | 3 (6) | 1 (5.9) | 2 (6) | 2 (10) | 0 |
| Acinetobacter baumannii, n (%) | 1 (2) | 0 | 1 (3) | 1 (5) | 0 |
| Klebsiella oxytoca, n (%) | 1 (2) | 1 (5.9) | 0 | 0 | 0 |
| Gram Positive, n (%) | 32 (66) | 9 (52.9) | 24 (72) | 14 (70) | 10 (77) |
| Staphylococcus epidermidis, n (%) | 11 (22) | 2 (11.8) | 9 (27) | 4 (20) | 5 (38.4) |
| Enterococcus faecalis, n (%) | 7 (14) | 1 (5.9) | 6 (18) | 5 (25) | 1 (7.6) |
| Staphylococcus capitis, n (%) | 5 (10) | 2 (11.8) | 3 (9) | 2 (10) | 1 (7.6) |
| Staphylococcus aureus, n (%) | 3 (6) | 1 (5.9) | 2 (6) | 0 | 2 (15.3) |
| Streptococci viridans, n (%) | 1 (2) | 0 | 1 (3) | 0 | 1 (7.6) |
| Enterococcus faecium, n (%) | 1 (2) | 0 | 1 (3) | 1 (5) | 0 |
| Staphylococcus hominis, n (%) | 1 (2) | 0 | 1 (3) | 1 (5) | 0 |
| Streptococcus mitis/oralis, n (%) | 1 (2) | 0 | 1 (3) | 1 (5) | 0 |
| Streptococcus agalactiae, n (%) | 2 (2) | 2 (11.8) | 0 | 0 | 0 |
| Fungal, n (%) | 6 (12) | 1 (5.9) | 5 (15) | 3 (15) | 2 (15.3) |
| Candida albicans, n (%) | 3 (12) | 0 | 3 (9) | 2 (10) | 1 (7.6) |
| Candida parapsilosis, n (%) | 3 (12) | 1 (5.9) | 2 (6) | 1 (5) | 1 (7.6) |
Abbreviations: NEC = necrotizing enterocolitis
The data presented as n (%).
In the surgical cohort, 9 neonates with NEC-associated positive blood cultures had polymicrobial infections. Organisms involved in the polymicrobial cultures were as follows: 1. Candida parapsilosis + Staphylococcus epidermidis; 2. Enterococcus faecalis + Staphylococcus capitis; 3. Escherichia coli + Candida albicans + Enterococcus faecalis; 4. Streptococci viridans + Staphylococcus capitis; 5. Enterococcus faecalis + Enterococcus faecium; 6. Enterococcus faecalis + Staphylococcus hominis; 7. Klebsiella pneumoniae + Enterococcus faecalis; 8. Klebsiella pneumoniae + Enterobacter cloacae; 9. Enterococcus faecalis + Staphylococcus epidermidis.